DocumentCode
3488264
Title
Ultra sensitive and compact VCSEL-based biosensor for detection of protein interactions and dengue antibodies
Author
Mateus, Carlos F R ; Huang, Michael C Y ; Parekh, Devang ; Chang-Hasnain, Connie J. ; Foley, Jonathan E. ; Lim, Wilfred O. ; Beatty, P. Robert ; Li, Peter ; Cunningham, Brian T.
Author_Institution
Electr. Eng. & Comput. Eng. Dept., California Univ., Berkeley, CA, USA
fYear
2004
fDate
28-30 June 2004
Abstract
We report a label-free biosensor system that consists of a tunable VCSEL, a plastic guided mode resonant filter and two pin detectors. The biosensor has´demonstrated the sensitivity of detecting antigen proteins concentration as low as Ipg/ml (6.7fM) and antibodies to dengue virus.
Keywords
biosensors; microorganisms; optical filters; proteins; surface emitting lasers; biosensor system; compact VCSEL; dengue antibody; dengue virus; detecting antigen proteins concentration; pin detector; plastic guided mode resonant filter; protein interaction detection; ultra sensitive; Biosensors; Mice; Optical filters; Optical surface waves; Proteins; Resonance; Time measurement; Tunable circuits and devices; Vertical cavity surface emitting lasers; Wavelength measurement;
fLanguage
English
Publisher
ieee
Conference_Titel
Biophotonics/Optical Interconnects and VLSI Photonics/WBM Microcavities, 2004 Digest of the LEOS Summer Topical Meetings
ISSN
1099-4742
Print_ISBN
0-7803-8306-0
Type
conf
DOI
10.1109/LEOSST.2004.1338664
Filename
1338664
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