Direct detection of Lyme disease by digital microscopy

Author

Hall, Thomas ; Bushmich, Sandra ; Krider, Hallie ; Fox, Martin

Author_Institution

Connecticut Univ., Storrs, CT, USA

fYear

1990

fDate

26-27 Mar 1990

Firstpage

61

Lastpage

62

Abstract

Studies were performed to test the hypothesis that an early direct diagnostic test for Lyme disease can be developed. This test involves automatic microscopic scanning of a relatively large volume of body fluids for the sparsely occurring Lyme disease causing agent, the spirochete bacterium Borrelia burgdorferi. Preliminary results indicate that segmentation, measurement, and classification techniques can be used to differentiate spirochetes from other materials in microscope images of blood smears stained with a fluorescent dye

Keywords

computerised picture processing; medical diagnostic computing; optical microscopy; patient diagnosis; Borrelia burgdorferi; Lyme disease; automatic microscopic scanning; blood smears; body fluids; classification; digital microscopy; direct diagnostic test; fluorescent dye; medical computer technique; segmentation; spirochete bacterium; Blood; Cameras; Diseases; Fluorescence; Image analysis; Image segmentation; Microscopy; Shape; System testing; Systems engineering and theory;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1990., Proceedings of the 1990 Sixteenth Annual Northeast

Conference_Location

State College, PA

Type

conf

DOI

10.1109/NEBC.1990.66289

Filename

66289