Title :
Evaluation of the dynamic mechanical behavior of polymer gel dosimeter
Author :
Vieira, S.L. ; Fatemi, M. ; Carneiro, A.A.O.
Author_Institution :
Inst. de Fis., Univ. Fed. de Goias, Goiânia, Brazil
fDate :
March 28 2011-April 1 2011
Abstract :
In this preliminary work, we present Magnetic Resonance Elastography (MRE) as a tool to study the mechanical properties of `MAGIC´ polymer-gel dosimeter. For this purpose, a set of gels were submitted to radiation doses from 10 to 30 Gy, and their responses to shear wave excitation were studied. We investigated the dynamic mechanical response (shear modulus) of the gel to driver frequency range of 100 to 250 Hz. The shear waves speeds in the gel were registered and converted to elastograms to show the radiation-induced changes in the elasticity distribution. To compare the elastograms behavior, parametric images of Nuclear Magnetic Resonance (NRM) spin-spin relaxation rate (R2=1/T2) were acquired and then converted to dose distribution maps. For the lowest and highest absorbed dose, a 2D correlation coefficient between these two imaging techniques ranged from 0.990 to 0.993, respectively. As expected, all gel dosimeters showed a monotonical increasing in its shear modulus as the values of absorbed dose and driver frequency increased. The results of this study showed that MRE elastograms have potential to visualize and quantify dose distribution in polymer gel dosimeters.
Keywords :
biomedical materials; dosimeters; elastic waves; elasticity; nuclear magnetic resonance; polymer gels; shear modulus; spin-spin relaxation; 2D correlation coefficient; MAGIC polymer-gel dosimeter; dose distribution maps; driver frequency; dynamic mechanical behavior; dynamic mechanical response; elasticity distribution; frequency 100 Hz to 250 Hz; magnetic resonance elastography; nuclear magnetic resonance; radiation absorbed dose 10 Gy to 30 Gy; radiation-induced changes; shear modulus; shear wave excitation; spin-spin relaxation rate; Biology; Containers; Driver circuits; Magnetic resonance imaging; Medical diagnostic imaging; Polymers; Dose Distribution; Dynamic Response; Gel dosimeter; MR Elastography; Shear Stiffness;
Conference_Titel :
Health Care Exchanges (PAHCE), 2011 Pan American
Conference_Location :
Rio de Janeiro
Print_ISBN :
978-1-61284-915-7
DOI :
10.1109/PAHCE.2011.5871906