Title :
Flip-drop: Droplet array created by surface energy trap for combinatorial screening
Author :
Yi Zhang ; Tza-Huei Wang
Abstract :
Here we present a droplet array platform named "flip-drop" that incorporates novel surface energy traps (SETs) to generate an array of droplets of combinatorial mixtures for bioanalytical screening. This droplet array platform is exemplified using a quantum-dot fluorescence resonance energy transfer (QD-FRET) sensing assay for detection of the RSF1 cancer biomarker.
Keywords :
biological techniques; biomedical transducers; cancer; drops; quantum dots; sensor arrays; surface energy; QD-FRET; RSF1 cancer biomarker detection; SET; bioanalytical screening; combinatorial mixture screening; droplet array platform generation; flip-drop; quantum-dot fluorescence resonance energy transfer sensing assay; surface energy trap; Arrays; Cancer; DNA; Fluorescence; Quantum dots; Sensors; Surface treatment;
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on
Conference_Location :
Taipei
Print_ISBN :
978-1-4673-5654-1
DOI :
10.1109/MEMSYS.2013.6474454
