The effects of extremely low frequency pulsed electromagnetic fields (ELF) on human lymphocyte proliferation in vitro and DNA repair

Author

Bersani, F. ; Franceschi, C. ; Monti, D. ; Bologni, A. ; Gatti, C. ; Cadossi, R. ; Nichelatti, M. ; Moschini, G. ; Cossarizza, A.

Author_Institution

Dept. of Phys., Bologna Univ., Italy

fYear

1988

fDate

4-7 Nov. 1988

Firstpage

906

Abstract

The effect of extremely-low-frequency electromagnetic fields on in-vitro mitogen-induced lymphocyte proliferation was studied in two groups of healthy subjects (23 and 85 years, mean ages). An increase of cell proliferation was observed to be much higher in the group of aged subjects. The effects depended on the mitogen dose and involved interleukin-2 production and/or utilization. The DNA repair capability and cell survival in the exposed cultures after gamma irradiation was also evaluated, and no genotoxic effect was found.<>

Keywords

DNA; biological effects of fields; biological effects of gamma-rays; biomolecular effects of radiation; blood; cellular effects of radiation; 23 to 85 yr; DNA repair; ELF; aged subjects; cell survival; exposed cultures; gamma irradiation; healthy subjects; human lymphocyte proliferation; in-vitro mitogen-induced lymphocyte proliferation; interleukin-2 production; low frequency pulsed electromagnetic fields;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE

Conference_Location

New Orleans, LA, USA

Print_ISBN

0-7803-0785-2

Type

conf

DOI

10.1109/IEMBS.1988.95245

Filename

95245