Typical problems and solutions in electrochemical measurement cell development

In this work we present typical problems and solutions concerning the development of prototyping electrochemical measurement cells for biosensoric applications. The influences of unwanted effects are discussed such as 1) the variation of gold thin film working electrode surface areas due to the technological inaccuracy of the laser ablation electrode patterning; 2) the variation of the working electrode areas exposed to the electrolyte due to the inaccurate positioning of the fluidic cell and 3) the electrolyte evaporation in the case of open measurement cells. Pilot design plans of a new electrochemical measurement platform fabricated by 3D Rapid Prototyping Technology (RPT) are also presented.