Development of Whole Human Genome Micro-array Automated Hybridization Platform

Author

Jiang, Jinq-Yu ; Lin, Kuo-Hsiung ; Chen, Chia-Chun ; Huang, Jie-Len ; Huang, Chun-Hung ; Su, Hung-Ju

Author_Institution

Ind. Technol. Res. Inst., Hsinchu

fYear

2007

fDate

22-25 Sept. 2007

Firstpage

640

Lastpage

645

Abstract

A micro-array based automated hybridization platform, ITRI HybOne, has been developed for whole human genome expression profiling test. According to the user-defined protocol, an operator can set the heating temperature, washing temperature, heating hours and washing hours before starting the profiling test. Operator inputs target samples and micro-arrays to ITRI HybOne and push the Cycle-Start button to start. After hours of automatic process, the micro-arrays are ready for profile scanning. The prototype platform has a throughput rate of 12-sets of hybridization per lot.

Keywords

automation; biology computing; biomedical equipment; computerised instrumentation; genetic engineering; genetics; Cycle-Start button; ITRI HybOne; genome expression profiling test; heating hours; heating temperature; micro-array automated hybridization platform; user-defined protocol; washing hours; washing temperature; whole human genome; Automation; Bioinformatics; Biomedical engineering; DNA; Genomics; Heating; Humans; Machining; Prototypes; Throughput;

fLanguage

English

Publisher

ieee

Conference_Titel

Automation Science and Engineering, 2007. CASE 2007. IEEE International Conference on

Conference_Location

Scottsdale, AZ

Print_ISBN

978-1-4244-1154-2

Electronic_ISBN

978-1-4244-1154-2

Type

conf

DOI

10.1109/COASE.2007.4341797

Filename

4341797