• DocumentCode
    3520725
  • Title

    Photometric method of estimation of coagulation process parameters

  • Author

    Nosova, Ekaterina V. ; Aristov, Alexander A. ; Nefedova, Natalia S.

  • Author_Institution
    Tomsk Polytech. Univ., Tomsk, Russia
  • fYear
    2015
  • fDate
    June 29 2015-July 3 2015
  • Firstpage
    586
  • Lastpage
    590
  • Abstract
    Article is devoted to the development of a new method of carrying out coagulation tests based on photometric study of bioliquid droplet samples. The initial methodology of carrying out experiments and the analysis of a shape of obtained photometric curves are given. It is defined that the most informative are the optical curves obtained at the receiver location in the optical focus of droplet test, formed after the coagulation process. Researches on improvement of the methodology of carrying out experiments in order to increase the sensitivity and repeatability of our method are presented. A methodology of reagent´s introduction to photometric cuvette was determined. A comparative analysis of the behavior of the photometric curves, depending on the method of reagent´s mixing is carried out. In process of determine the optimal characteristics of the optical system, it is found that the highest sensitivity is achieved by using small angular apertures of the receiving device.
  • Keywords
    bio-optics; biological specimen preparation; biomedical measurement; blood; coagulation; drops; mixing; photometry; bioliquid droplet sample; coagulation parameter estimation; coagulation test; comparative analysis; droplet test; optical curve; optical focus; optimal optical system characteristics; photometric curve shape analysis; photometric cuvette; photometric method; reagent introduction; reagent mixing dependence; receiving device small angular aperture; repeatability; sensitivity; Apertures; Coagulation; Optical mixing; Optical receivers; Optical sensors; Optical variables control; Plasmas; coagulation; drop; fibrin clot; plasma; tehplastin;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro/Nanotechnologies and Electron Devices (EDM), 2015 16th International Conference of Young Specialists on
  • Conference_Location
    Erlagol
  • ISSN
    2325-4173
  • Print_ISBN
    978-1-4673-6718-9
  • Type

    conf

  • DOI
    10.1109/EDM.2015.7184611
  • Filename
    7184611