DocumentCode :
3522430
Title :
A comparison of categorisation algorithms for predicting the cellular localization sites of proteins
Author :
Cairns, Paul ; Huyck, Christian ; Mitchell, Ian ; Wu, Wendy Xihyu
Author_Institution :
Sch. of Comput. Sci., Middllesex Univ., London, UK
fYear :
2001
fDate :
2001
Firstpage :
296
Lastpage :
300
Abstract :
A previous attempt to categorize yeast proteins based on certain attributes yielded only a 55% success rate of correct categorisation using a new type of decision procedure. This paper considers using existing soft computing approaches to improve the categorisation. More specifically, learning algorithms based on neural networks, growing cell systems, a rule development algorithm and genetic algorithms are applied to the yeast data. All of the results are at least as good as the original data showing that new problems do not necessarily require new algorithms. More interestingly as a consequence of using different algorithms, a consistent failure to achieve high success rates actually indicates features of the data rather than the failings of one or other of the algorithms
Keywords :
biology computing; feedforward neural nets; genetic algorithms; learning (artificial intelligence); proteins; categorisation; cellular localization; feedforward neural networks; genetic algorithms; growing cell structures; learning algorithms; yeast protein; Clustering algorithms; Fungi; Genetics; Humans; Neural networks; Prediction algorithms; Proteins; Spatial databases; Testing; Unsupervised learning;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Database and Expert Systems Applications, 2001. Proceedings. 12th International Workshop on
Conference_Location :
Munich
Print_ISBN :
0-7695-1230-5
Type :
conf
DOI :
10.1109/DEXA.2001.953078
Filename :
953078
Link To Document :
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