DocumentCode
3522430
Title
A comparison of categorisation algorithms for predicting the cellular localization sites of proteins
Author
Cairns, Paul ; Huyck, Christian ; Mitchell, Ian ; Wu, Wendy Xihyu
Author_Institution
Sch. of Comput. Sci., Middllesex Univ., London, UK
fYear
2001
fDate
2001
Firstpage
296
Lastpage
300
Abstract
A previous attempt to categorize yeast proteins based on certain attributes yielded only a 55% success rate of correct categorisation using a new type of decision procedure. This paper considers using existing soft computing approaches to improve the categorisation. More specifically, learning algorithms based on neural networks, growing cell systems, a rule development algorithm and genetic algorithms are applied to the yeast data. All of the results are at least as good as the original data showing that new problems do not necessarily require new algorithms. More interestingly as a consequence of using different algorithms, a consistent failure to achieve high success rates actually indicates features of the data rather than the failings of one or other of the algorithms
Keywords
biology computing; feedforward neural nets; genetic algorithms; learning (artificial intelligence); proteins; categorisation; cellular localization; feedforward neural networks; genetic algorithms; growing cell structures; learning algorithms; yeast protein; Clustering algorithms; Fungi; Genetics; Humans; Neural networks; Prediction algorithms; Proteins; Spatial databases; Testing; Unsupervised learning;
fLanguage
English
Publisher
ieee
Conference_Titel
Database and Expert Systems Applications, 2001. Proceedings. 12th International Workshop on
Conference_Location
Munich
Print_ISBN
0-7695-1230-5
Type
conf
DOI
10.1109/DEXA.2001.953078
Filename
953078
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