• DocumentCode
    3522430
  • Title

    A comparison of categorisation algorithms for predicting the cellular localization sites of proteins

  • Author

    Cairns, Paul ; Huyck, Christian ; Mitchell, Ian ; Wu, Wendy Xihyu

  • Author_Institution
    Sch. of Comput. Sci., Middllesex Univ., London, UK
  • fYear
    2001
  • fDate
    2001
  • Firstpage
    296
  • Lastpage
    300
  • Abstract
    A previous attempt to categorize yeast proteins based on certain attributes yielded only a 55% success rate of correct categorisation using a new type of decision procedure. This paper considers using existing soft computing approaches to improve the categorisation. More specifically, learning algorithms based on neural networks, growing cell systems, a rule development algorithm and genetic algorithms are applied to the yeast data. All of the results are at least as good as the original data showing that new problems do not necessarily require new algorithms. More interestingly as a consequence of using different algorithms, a consistent failure to achieve high success rates actually indicates features of the data rather than the failings of one or other of the algorithms
  • Keywords
    biology computing; feedforward neural nets; genetic algorithms; learning (artificial intelligence); proteins; categorisation; cellular localization; feedforward neural networks; genetic algorithms; growing cell structures; learning algorithms; yeast protein; Clustering algorithms; Fungi; Genetics; Humans; Neural networks; Prediction algorithms; Proteins; Spatial databases; Testing; Unsupervised learning;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Database and Expert Systems Applications, 2001. Proceedings. 12th International Workshop on
  • Conference_Location
    Munich
  • Print_ISBN
    0-7695-1230-5
  • Type

    conf

  • DOI
    10.1109/DEXA.2001.953078
  • Filename
    953078