DocumentCode :
3533024
Title :
Surface modification of superparamagnetic iron oxide nanoparticles for clinical applications
Author :
Woo, K. ; Hong, Jonggi
Author_Institution :
Nano-Materials Res. Center, Korea Inst. of Sci. & Technol., Seoul, South Korea
fYear :
2005
fDate :
4-8 April 2005
Firstpage :
799
Lastpage :
800
Abstract :
Monodisperse superparamagnetic iron oxide nanoparticles (SPIONs) were prepared by thermal decomposition of Fe(CO)5 and by consecutive aeration in organic medium. The resultant hydrophobic SPION surface was modified to be hydrophilic via Fe-S covalent bond with bi-functional mercaptopropionic acid (MPA, HSCH2CH2COOH) and then, the terminal carboxylic acid group was esterified with dextran for biocompatibility. Analysis by water dispersity, TEM, XRD, and FT-IR is discussed.
Keywords :
Fourier transform spectra; X-ray diffraction; infrared spectra; iron compounds; nanoparticles; nanotechnology; pyrolysis; superparamagnetism; surface treatment; transmission electron microscopy; FTIR; Fe2O3; TEM; XRD; aeration; bifunctional mercaptopropionic acid; biocompatibility; dextran; monodisperse superparamagnetic iron oxide nanoparticles; surface modification; terminal carboxylic acid group; thermal decomposition; water dispersity; Bonding; Iron; Nanoparticles; Polymers; Protection; Stability; Thermal decomposition; Virtual manufacturing; Water; X-ray scattering;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Magnetics Conference, 2005. INTERMAG Asia 2005. Digests of the IEEE International
Print_ISBN :
0-7803-9009-1
Type :
conf
DOI :
10.1109/INTMAG.2005.1463828
Filename :
1463828
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=3533024
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