Title :
Integrated photonic structures for efficient, massively-parallel collection of directional single-molecule fluorescence
Author :
Grot, Annette ; Rulison, Aaron ; Hsiung, Pei-Lin ; Cheng, Janice ; Tomaney, Austin ; Saxena, Ravi ; Lundquist, Paul ; Turner, Stephen W.
Author_Institution :
Pacific Biosci., Menlo Park, CA, USA
Abstract :
A conical micromirror is shown to increase the signal from fluorescent molecules within a collocated subwavelength metal aperture by 5×. Large-scale integration (75,000 miromirrors/aperture pairs) is demonstrated.
Keywords :
biological techniques; fluorescence; integrated optics; micromirrors; optical arrays; collocated subwavelength metal aperture; conical micromirror; directional single molecule fluorescence; fluorescent molecules; integrated photonic structures; massively parallel fluorescence collection; Biomedical optical imaging; Fluorescence; Micromirrors; Optical device fabrication; Optical imaging; Stimulated emission; Substrates;
Conference_Titel :
Optical MEMS and Nanophotonics (OMN), 2012 International Conference on
Conference_Location :
Banff, AB
Print_ISBN :
978-1-4577-1511-2
DOI :
10.1109/OMEMS.2012.6318805
