A magnetic molecule detection system - a comparison of different setups by computer simualtion

Author

Schepper, W. ; Schotter, J. ; Bruckl, H. ; Reiss, G.

Author_Institution

Dept. of Phys., Bielefeld Univ.

fYear

2005

fDate

4-8 April 2005

Firstpage

927

Lastpage

927

Abstract

A new scheme of combined movement by on-chip currents and detection of magnetically labeled biomolecules has been introduced. This was the first step on the way to an on-chip laboratory. A conductor pair has been placed to this end on both sides of the sensor with the possibility of parallel or series connection. This connector setup made it possible to magnetize the beads and move them over the sensor area. This bead motion caused the detection signal. Magnetoresistance curves were measured and micromagnetic calculations have been done for the sensor types: giant magnetoresistance and tunneling magnetoresistance. The results showed an increase in sensitivity and also a corresponding change in the GMR curve. This therefore established an ideal sensor for the bead detection up to large values of bead surface concentration

Keywords

giant magnetoresistance; magnetic sensors; magnetisation; micromagnetics; tunnelling magnetoresistance; bead surface concentration; conductor pair; detection signal; giant magnetoresistance; magnetic molecule detection system; magnetically labeled biomolecules; magnetization; magnetoresistance curves; micromagnetic calculations; on-chip currents; parallel connection; sensor; series connection; tunneling magnetoresistance; Biosensors; Conductors; Giant magnetoresistance; Laboratories; Magnetic sensors; Molecular biophysics; Motion detection; Signal detection; Tunneling magnetoresistance;

fLanguage

English

Publisher

ieee

Conference_Titel

Magnetics Conference, 2005. INTERMAG Asia 2005. Digests of the IEEE International

Conference_Location

Nagoya

Print_ISBN

0-7803-9009-1

Type

conf

DOI

10.1109/INTMAG.2005.1464360

Filename

1464360