DocumentCode
3541355
Title
Causal compressive sensing for gene network inference
Author
Deng, Mo ; Emad, Amin ; Milenkovic, Olgica
Author_Institution
Univ. of Illinois, Urbana-Champaign, Urbana, IL, USA
fYear
2012
fDate
5-8 Aug. 2012
Firstpage
696
Lastpage
699
Abstract
We propose a novel framework for studying causal inference of gene interactions using a combination of compressive sensing and Granger causality techniques. The gist of the approach is to discover sparse linear dependencies between time series of gene expressions via a Granger-type elimination method. The method is tested on the Gardner dataset for the SOS network in E. coli, for which both known and unknown causal relationships are discovered.
Keywords
causality; compressed sensing; inference mechanisms; signal reconstruction; time series; E. coli; Gardner dataset; Granger causality technique; Granger-type elimination method; SOS network; causal compressive sensing; causal inference; gene network inference interaction; sparse linear dependency; time series; Amplitude modulation; Compressed sensing; Gene expression; Sensors; Testing; Time series analysis; Vectors; Compressive sensing; Gene Expression; Granger Causality; SOS Network;
fLanguage
English
Publisher
ieee
Conference_Titel
Statistical Signal Processing Workshop (SSP), 2012 IEEE
Conference_Location
Ann Arbor, MI
ISSN
pending
Print_ISBN
978-1-4673-0182-4
Electronic_ISBN
pending
Type
conf
DOI
10.1109/SSP.2012.6319797
Filename
6319797
Link To Document