• DocumentCode
    3541355
  • Title

    Causal compressive sensing for gene network inference

  • Author

    Deng, Mo ; Emad, Amin ; Milenkovic, Olgica

  • Author_Institution
    Univ. of Illinois, Urbana-Champaign, Urbana, IL, USA
  • fYear
    2012
  • fDate
    5-8 Aug. 2012
  • Firstpage
    696
  • Lastpage
    699
  • Abstract
    We propose a novel framework for studying causal inference of gene interactions using a combination of compressive sensing and Granger causality techniques. The gist of the approach is to discover sparse linear dependencies between time series of gene expressions via a Granger-type elimination method. The method is tested on the Gardner dataset for the SOS network in E. coli, for which both known and unknown causal relationships are discovered.
  • Keywords
    causality; compressed sensing; inference mechanisms; signal reconstruction; time series; E. coli; Gardner dataset; Granger causality technique; Granger-type elimination method; SOS network; causal compressive sensing; causal inference; gene network inference interaction; sparse linear dependency; time series; Amplitude modulation; Compressed sensing; Gene expression; Sensors; Testing; Time series analysis; Vectors; Compressive sensing; Gene Expression; Granger Causality; SOS Network;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Statistical Signal Processing Workshop (SSP), 2012 IEEE
  • Conference_Location
    Ann Arbor, MI
  • ISSN
    pending
  • Print_ISBN
    978-1-4673-0182-4
  • Electronic_ISBN
    pending
  • Type

    conf

  • DOI
    10.1109/SSP.2012.6319797
  • Filename
    6319797