Title :
CMOS sensor array for electrical imaging of neuronal activity
Author :
Eversmann, Bjeorn ; Jenkner, Martin ; Hofmann, Franz ; Paulus, Christian ; Holzapfl, Birgit ; Thewes, Roland ; Schmitt-Landsiedel, Doris ; Lambacher, Armin ; Kaul, Alexander ; Zeitler, Ralf ; Merz, Mathhias ; Junze, A. ; Fromhrz, P.
Author_Institution :
Corporate Res., Infineon Technol. AG, Munich, Germany
Abstract :
A CMOS sensor array for extracellular, high density imaging of electrical activity of living neural networks is presented. The chip is fabricated in an extended 0.5 μm CMOS technology, and provides 128 × 128 pixels with a pitch of 7.8 pm; full frame rate is 2000 frames per second. Dynamic maps from single cells and cultured networks are shown.
Keywords :
CMOS integrated circuits; biomedical imaging; biosensors; neurophysiology; 0.5 micron; 128 pixel; 16384 pixel; CMOS sensor array; electrical imaging; extracellular high density imaging; living neural networks; neuronal activity; Biomembranes; Biosensors; CMOS image sensors; CMOS technology; Electrodes; Extracellular; Integrated circuit interconnections; Neurons; Sensor arrays; Voltage;
Conference_Titel :
Circuits and Systems, 2005. ISCAS 2005. IEEE International Symposium on
Print_ISBN :
0-7803-8834-8
DOI :
10.1109/ISCAS.2005.1465378