DocumentCode
3547111
Title
Highly sensitive protein detection using quenching effects from aptamer-functionalized photonic crystals
Author
Choi, Yuri ; Choi, Eunpyo ; Park, Jungyul
Author_Institution
Interdiscipl. Program of Integrated Biotechnol., Sogang Univ., Seoul, South Korea
fYear
2012
fDate
Jan. 29 2012-Feb. 2 2012
Firstpage
839
Lastpage
841
Abstract
This paper proposes a new technique for protein detection using quenching effects from aptamer-functionalized photonic crystals. The surface of hydrogel based inverse opal structures are functionalized with aptamers and they are hybridized with quenchers. Then, target protein (thrombin) can be selectively, sensitively detected by monitoring the change of both intensity and color (change of reflective wavelength).
Keywords
biosensors; hydrogels; molecular biophysics; photonic crystals; proteins; aptamer-functionalized photonic crystals; highly sensitive protein detection; hydrogel based inverse opal structures; quenching effects; Biomedical optical imaging; Biosensors; DNA; Image color analysis; Optical reflection; Photonic crystals;
fLanguage
English
Publisher
ieee
Conference_Titel
Micro Electro Mechanical Systems (MEMS), 2012 IEEE 25th International Conference on
Conference_Location
Paris
ISSN
1084-6999
Print_ISBN
978-1-4673-0324-8
Type
conf
DOI
10.1109/MEMSYS.2012.6170316
Filename
6170316
Link To Document