Development of minimally invasive microdialysis needle for continuous monitoring of biological substances

Author

Tsuruoka, N. ; Ishii, K. ; Matsunaga, T. ; Nagatomi, R. ; Haga, Y.

Author_Institution

Tohoku Univ., Sendai, Japan

fYear

2012

fDate

Jan. 29 2012-Feb. 2 2012

Firstpage

941

Lastpage

944

Abstract

Concentrations of biological substances are useful as indicator of our health. In order to monitor biological substances, the minimally invasive device which does microdialysis in subepidermal tissue has been developed. Microdialysis needle has flow channel with dialysis membrane. It has been fabricated around a thin steel needle by our developed non-planer photofabrication process. Because this process is additionally applied, several shaped tubes and wires can be used as a base substance. Animal experiment was performed using mouse. Lactate concentration was measured as one of biological substance. Lactate was successfully collected with this needle.

Keywords

biomedical equipment; needles; organic compounds; patient monitoring; animal experiment; biological substances concentrations; continuous monitoring; dialysis membrane; flow channel; lactate concentration; minimally invasive microdialysis needle; mouse; subepidermal tissue; thin steel needle; Blood; Mice; Monitoring; Needles; Sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro Electro Mechanical Systems (MEMS), 2012 IEEE 25th International Conference on

Conference_Location

Paris

ISSN

1084-6999

Print_ISBN

978-1-4673-0324-8

Type

conf

DOI

10.1109/MEMSYS.2012.6170341

Filename

6170341