• DocumentCode
    3547222
  • Title

    “Neural bypass” with hydrogel microfiber encapsulating neurons

  • Author

    Kato-Negishi, Midori ; Onoe, Hiroaki ; Takeuchi, Shoji

  • Author_Institution
    Inst. of Ind. Sci., Univ. of Tokyo, Tokyo, Japan
  • fYear
    2012
  • fDate
    Jan. 29 2012-Feb. 2 2012
  • Firstpage
    977
  • Lastpage
    980
  • Abstract
    This paper describes a “neural bypass” formed by hydrogel microfiber encapsulating neurons and glial cells. Using this bypass, we developed a technique to connect the separated neuronal regions without cell damage. We also demonstrated that a completely-transected cortical network was connected with the neural bypass. We believe that our neural bypass would be an extremely effective tool to connect damaged neuronal networks in the neurodegenerative diseases: cerebral infarction, stroke, brain trauma, Alzheimer´s disease.
  • Keywords
    brain; cellular biophysics; diseases; hydrogels; injuries; neurophysiology; Alzheimer disease; brain trauma; cerebral infarction; completely-transected cortical network; damaged neuronal network; glial cells; hydrogel microfiber; neural bypass; neurodegenerative diseases; neuronal region; stroke; Biological neural networks; Cells (biology); Fluorescence; Glass; Microscopy; Nerve fibers;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro Electro Mechanical Systems (MEMS), 2012 IEEE 25th International Conference on
  • Conference_Location
    Paris
  • ISSN
    1084-6999
  • Print_ISBN
    978-1-4673-0324-8
  • Type

    conf

  • DOI
    10.1109/MEMSYS.2012.6170349
  • Filename
    6170349