Title :
Near-field single molecule spectroscopy
Author :
Lu, Pingping ; Bian, R. ; Sanchez, E. ; Leung, P.
Abstract :
Recent advances in near-field scanning optical microscopy (NSOM) make it possible to image single molecule emission with nanometric resolution and extend the single molecule spectroscopy work done at cryogenic temperature to the room temperature regime. With NSOM, molecular fluorescence can be spectrally and temporally resolved, allowing detailed studies of molecular interaction and dynamics on a single molecule basis with a spatial resolution beyond the diffraction limit.
Keywords :
fluorescence spectroscopy; molecular biophysics; optical microscopy; cryogenic temperature; diffraction limit; molecular dynamics; molecular fluorescence; molecular interaction; nanometric resolution; near-field scanning optical microscopy; near-field single molecule spectroscopy; room temperature regime; single molecule basis; single molecule emission; spatial resolution; Biomembranes; Dark states; Fluorescence; Glass; Laboratories; Optical microscopy; Spatial resolution; Spectroscopy; Stimulated emission; Temperature;
Conference_Titel :
Quantum Electronics and Laser Science Conference, 1996. QELS '96., Summaries of Papers Presented at the
Conference_Location :
Anaheim, CA, USA
Print_ISBN :
1-55752-444-0
