In-beam PET imaging for the control of heavy-ion tumour therapy

Author

Pawelke, J. ; Enghardt, W. ; Haberer, Th ; Hasch, B.G. ; Hinz, R. ; Kr?¤mer, M. ; Lauckner, K. ; Sobiella, M.

Author_Institution

Inst. fur Kern- u. Hadronenphys., Forschungszentrum Rossendorf, Dresden, Germany

Volume

2

fYear

1996

Firstpage

1099

Abstract

A method for the in-situ control of the heavy-ion tumour therapy by means of positron emission tomography is introduced. This method is founded on the measurement of the dynamic spatial distribution of β ⁺-emitters generated by nuclear fragmentation during the irradiation and the relationship between the spatial distributions of the β⁺-radioactivity and the dose. In order to study this relationship and to arrive at deducing the dose distribution from the measured β⁺-activity distribution a framework of model calculations is used. Results of phantom experiments with ¹²C ion beams are presented, demonstrating the good agreement between experiment and simulation as well as the possibilities and limits of treatment plan verification and beam monitoring

Keywords

dosimetry; positron emission tomography; radiation therapy; β⁺-emitters; β⁺-radioactivity; ¹²C ion beams; beam monitoring; dose distribution; dynamic spatial distribution; heavy-ion tumour therapy; in-beam PET imaging; in-situ control; nuclear fragmentation; positron emission tomography; spatial distributions; treatment plan verification; Data mining; Imaging phantoms; Ion beams; Medical treatment; Monitoring; Nuclear measurements; Positron emission tomography; Shape; Synchrotrons; Tumors;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium, 1996. Conference Record., 1996 IEEE

ISSN

1082-3654

Print_ISBN

0-7803-3534-1

Type

conf

DOI

10.1109/NSSMIC.1996.591573

Filename

591573