Title :
In-beam PET imaging for the control of heavy-ion tumour therapy
Author :
Pawelke, J. ; Enghardt, W. ; Haberer, Th ; Hasch, B.G. ; Hinz, R. ; Kr?¤mer, M. ; Lauckner, K. ; Sobiella, M.
Author_Institution :
Inst. fur Kern- u. Hadronenphys., Forschungszentrum Rossendorf, Dresden, Germany
Abstract :
A method for the in-situ control of the heavy-ion tumour therapy by means of positron emission tomography is introduced. This method is founded on the measurement of the dynamic spatial distribution of β +-emitters generated by nuclear fragmentation during the irradiation and the relationship between the spatial distributions of the β+-radioactivity and the dose. In order to study this relationship and to arrive at deducing the dose distribution from the measured β+-activity distribution a framework of model calculations is used. Results of phantom experiments with 12 C ion beams are presented, demonstrating the good agreement between experiment and simulation as well as the possibilities and limits of treatment plan verification and beam monitoring
Keywords :
dosimetry; positron emission tomography; radiation therapy; β+-emitters; β+-radioactivity; 12C ion beams; beam monitoring; dose distribution; dynamic spatial distribution; heavy-ion tumour therapy; in-beam PET imaging; in-situ control; nuclear fragmentation; positron emission tomography; spatial distributions; treatment plan verification; Data mining; Imaging phantoms; Ion beams; Medical treatment; Monitoring; Nuclear measurements; Positron emission tomography; Shape; Synchrotrons; Tumors;
Conference_Titel :
Nuclear Science Symposium, 1996. Conference Record., 1996 IEEE
Print_ISBN :
0-7803-3534-1
DOI :
10.1109/NSSMIC.1996.591573
