DocumentCode :
3569053
Title :
A novel method for 3D prostate MR-histology registration using anatomical landmarks
Author :
Hughes, Cecilia ; Rouviere, Olivier ; Mege-Lechevallier, Florence ; Souchon, Remi ; Prost, Remy
Author_Institution :
CCITI, Dijon, France
fYear :
2012
Firstpage :
2591
Lastpage :
2594
Abstract :
No current imaging technique is capable of detecting with precision tumours within the prostate. To evaluate each technique, the histology data must be registered to the imaged data. As the histology slices cannot be assumed to be cut along the same plane as the imaged data was acquired, the registration must be considered as a 3D problem. We propose a novel 3D registration method which uses the ejaculatory ducts, an anatomical landmark present in every prostate and visible in both MR and histology. The method has been tested on 3 prostate specimens. The aligned histology slices are first shear corrected, with an average angular error after correction of 2.83±1.46°. The MR-histology registration accuracy, evaluated operator-independently, is on average 1.50 ± 0.74 mm.
Keywords :
biological tissues; image registration; medical image processing; tumours; 3D prostate MR-histology registration; MR-histology registration accuracy; aligned histology slices; anatomical landmarks; ejaculatory ducts; histology data; histology slices; imaged data; imaging technique; precision tumour detection; prostate specimens; Ducts; Imaging; In vivo; Needles; Prostate cancer; Vectors; Histology; MRI; Prostate; Registration;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Signal Processing Conference (EUSIPCO), 2012 Proceedings of the 20th European
ISSN :
2219-5491
Print_ISBN :
978-1-4673-1068-0
Type :
conf
Filename :
6334153
Link To Document :
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