A new OCT-based method to generate virtual maps of vitreomacular interface pathologies

Optical coherence tomography (OCT) is the most accurate modality for noninvasive assessment of vitreoretinal interface (VRI). The scientific objective of research presented in this paper was to develop a new OCT-based method for investigation of vitreomacular interface pathologies in human eyes. We propose a new approach for the automatic generation of virtual maps representing the distance between the posterior surface of the hyaloid (PSH) and the inner limiting membrane (ILM) in the vitreomacular traction (VMT) pathology. Volumetric data was acquired from 3 adult patients with VMT. OCT B-scans were processed frame-by-frame and refined by advanced digital imaging algorithms, including application of the graph analysis approach, that allow for plausible segmentation of epiretinal pathologies and retinal surface. We are able to precisely segment and quantify VMTs in all subjects. The resulting virtual maps show a potential to evolve into a new useful tool for eye doctors that can support clinical decisions.