Title :
Inhomogeneous anisotropic bidomain modeling of cardiac tissue
Author :
Saleheen, Hasan I. ; Ng, Kwong T.
Author_Institution :
Concurrent Technol. Corp., Johnstown, PA, USA
Abstract :
In this paper we describe a new finite difference bidomain formulation for a cardiac tissue with intramural fiber rotation. The cardiac tissue consists of discrete layers of fibers arranged at different angular orientations within the tissue. The angular rotation of the fiber creates anisotropy in the tissue´s intracellular and interstitial conductivities which vary from one layer to another, i.e., inhomogeneous. The new inhomogeneous anisotropic bidomain formulation will allow a more realistic modeling of the cardiac tissue. Mathematical formulation of the new method and its validation are presented.
Keywords :
Laplace equations; bioelectric phenomena; biomembrane transport; cardiology; finite difference methods; muscle; physiological models; Dirichlet boundary conditions; Laplace equations; angular rotation; cardiac tissue; conductivity anisotropy; different angular orientations; discrete layers of fibers; finite difference bidomain formulation; inhomogeneous anisotropic bidomain modeling; interstitial conductivity; intracellular conductivity; intramural fiber rotation; realistic modeling; Anisotropic magnetoresistance; Biomembranes; Cardiac tissue; Conductivity; Difference equations; Extracellular; Finite difference methods; Laplace equations; Myocardium; Tensile stress;
Conference_Titel :
Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE
Print_ISBN :
0-7803-4262-3
DOI :
10.1109/IEMBS.1997.754506
