Title :
A preliminary study on mathematical modeling of protein synthesis process
Author :
Gao, Rui ; Yu, Juanyi ; Zhang, Mingjun ; Tarn, Tzyh-Jong
Author_Institution :
Sch. of Control Sci. & Eng., Shandong Univ., Ji´´nan, China
Abstract :
This paper proposes a mathematical formulation for the process of protein synthesis. The goal is to mathematically describe and interpret the genetic information flow from DNA to RNA, and to protein molecules. Matrix theory is extensively utilized to represent key concepts related to DNA hybridization, RNA self-hybridization, and polarities of the amino acids. Propositions and a complete mathematical formulation for protein synthesis procedure based on the models are presented. We hope that this work could lay a mathematical foundation for introducing system and control theories into genomics.
Keywords :
DNA; biology computing; genetics; genomics; matrix algebra; molecular biophysics; proteins; DNA hybridization; RNA self-hybridization; amino acid; genetic information flow; genomics; matrix theory; protein molecules; protein synthesis process; Amino acids; Bioinformatics; Control system synthesis; Control theory; DNA; Genetics; Genomics; Mathematical model; Proteins; RNA; DNA hybridization; Protein synthesis; RNA self-hybridization; mathematical modeling; the Central Dogma;
Conference_Titel :
Intelligent Computing and Intelligent Systems, 2009. ICIS 2009. IEEE International Conference on
Print_ISBN :
978-1-4244-4754-1
Electronic_ISBN :
978-1-4244-4738-1
DOI :
10.1109/ICICISYS.2009.5358375