Title :
Multispectral time-resolved diffuse optical tomography system for absorber mapping in turbid medium using wide-field single-pixel camera
Author :
Qi Pian ; Ruoyang Yao ; Intes, Xavier
Author_Institution :
Biomed. Eng. Dept., Rensselaer Polytech. Inst., Troy, NY, USA
Abstract :
In this work, we present the recent developments of our time-resolved diffuse optical system based on wide-field multispectral illumination and single-pixel detection scheme. The performance of the system for mapping 3D fluorophore or chromophore distribution with spectral contrast in turbid media is validated with improved quantification accuracy and reduced crosstalk.
Keywords :
CCD image sensors; biological tissues; biomedical optical imaging; fluorescence; light absorption; lighting; optical tomography; organic compounds; time resolved spectra; 3D chromophore distribution mapping; 3D fluorophore distribution mapping; light absorption mapping; multispectral time-resolved diffuse optical tomography system; single-pixel detection scheme; turbid medium; wide-field multispectral illumination; wide-field single-pixel camera; Biomedical optical imaging; Fluorescence; Optical crosstalk; Optical imaging; Optimized production technology; Tomography; Fö rster resonance energy transfer (FRET); compressive sensing; lifetime imaging; optical tomography; single-pixel camera; time-resolved imaging;
Conference_Titel :
Biomedical Engineering Conference (NEBEC), 2015 41st Annual Northeast
Print_ISBN :
978-1-4799-8358-2
DOI :
10.1109/NEBEC.2015.7117186
