Role of geometry in the endocardial electrocardiographic inverse problem

The authors investigated the effects of variations in volume conductor geometry on left ventricular endocardial potentials computed from cavitary potentials that were measured with the use of a noncontact, multi-electrode probe (the inverse problem). They found that simplifying the endocardial surface by using idealized approximations and applying spatial regularization to solve the inverse problem significantly improved the quality of the endocardial potentials. However, computed endocardial potentials were highly sensitive to errors in probe position