DocumentCode :
3595257
Title :
Initial results from a PET/planar small animal imaging system
Author :
Siegel, S. ; Vaquero, J.J. ; Aloj, L. ; Seidel, J. ; Jagoda, E. ; Gandler, W.R. ; Eckelman, W.C. ; Green, M.V.
Author_Institution :
Dept. of Nucl. Med., Nat. Inst. of Health, Bethesda, MD, USA
Volume :
2
fYear :
1998
fDate :
6/20/1905 12:00:00 AM
Firstpage :
1274
Abstract :
A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm×45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice
Keywords :
biological techniques; positron emission tomography; radioisotope imaging; ECG gating capability; PET/planar small animal imaging system; biological research instrumentation; genetically altered mice; normal mice; positron-emitting radiotracers; stationary opposed scintillation detectors pair; time coincidence; tomographic images; tracer transport; useful field-of-view; Animals; Bismuth; Crystals; Mice; Photomultipliers; Position sensitive particle detectors; Positron emission tomography; Scintillation counters; Sensor arrays; Solid scintillation detectors;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium, 1998. Conference Record. 1998 IEEE
ISSN :
1082-3654
Print_ISBN :
0-7803-5021-9
Type :
conf
DOI :
10.1109/NSSMIC.1998.774389
Filename :
774389
Link To Document :
بازگشت