Dynamic behaviour of a population of ionic channels in heart tissue

In monitoring and pacing of heart muscle excitation, further instrumentation requires a more profound biochemical description. The dynamic properties of the ionic flux through voltage dependent ionic channels are most important for the spreading of electrical excitation in a carpet of cells in the myocardium. Modelling of the time behaviour of ionic currents, especially of the transient effect at the beginning of a depolarization, is based upon data from single channel measurements with a patch clamp technique. The model covers the complete range of membrane potentials from resting potential to the strong hyperpolarization with continued parameterization