Title :
Calcium transient in cardiac cells during discontinuous conduction
Author :
Wagner, Mary B. ; Joyner, Ronald W.
Author_Institution :
Dept. of Pediatrics, Emory Univ., Atlanta, GA, USA
fDate :
6/21/1905 12:00:00 AM
Abstract :
We have combined the ability to monitor intracellular calcium in an isolated cardiac cell using confocal scanning laser fluorescence microscopy with “coupling clamp” technique which allows action potential (AP) propagation from the real cell to a real-time simulation of a model cell. We found that discontinuous conduction increases the intracellular calcium (Ca2+) transient
Keywords :
bioelectric potentials; biological techniques; biomembrane transport; calcium; cardiology; digital simulation; fluorescence; optical microscopy; physiological models; Ca; action potential propagation; confocal scanning laser fluorescence microscopy; coupling clamp technique; discontinuous conduction; intracellular Ca; intracellular Ca2+ transient; isolated cardiac cell; model cell; real cell; real-time simulation; Argon; Calcium; Clamps; Iron; Laser modes; Voltage;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802192
