CW THz spectroscopy of alanyl valine and valyl alanine

Author

Siegrist, K. ; Podobedov, V. ; Schwarzkopf, A. ; Pfefferkorn, C. ; Plusquellic, D.F.

Author_Institution

Nat. Inst. of Stand. & Technol., Gaithersburg, MD

fYear

2007

Firstpage

88

Lastpage

90

Abstract

CW THz spectroscopy has been used to investigate the lowest frequency vibrational modes of a pair of isostructural dipeptide nanotubes. THz spectra were obtained from 2 cm^-1 to 100 cm^-1 at 4.2 K for several different preparations of alanyl valine and valyl alanine, as a means of studying effects of cocrystallized solvent molecules on the spectra of these hydrophobic nanotubes. Removal of water or other solvent molecules from the flexible pores of the alanyl valine hydrophobic nanotubes resulted in shifts of a few cm^-1 in the apparent positions of some spectral features. For valyl alanine, spectral changes are even smaller, reflecting the lessened impact of hydrophobic interactions on the stronger H-bonding network of this dipeptide.

Keywords

biochemistry; biological techniques; hydrogen bonds; nanobiotechnology; nanotubes; organic compounds; submillimetre wave spectra; vibrational states; CW THz spectroscopy; H-bonding network; alanyl valine; cocrystallized solvent molecules; flexible pores; hydrophobic interactions; hydrophobic nanotubes; isostructural dipeptide nanotubes; temperature 4.2 K; valyl alanine; vibrational modes; wave number 2 cm^-1 to 100 cm^-1; Absorption; Amino acids; Artificial intelligence; Bonding; Crystallization; Frequency; Nanotubes; Peptides; Solvents; Spectroscopy; Biomolecules; CW THz spectroscopy; hydrophobic solvent interactions; nanotubes; peptides;

fLanguage

English

Publisher

ieee

Conference_Titel

Infrared and Millimeter Waves, 2007 and the 2007 15th International Conference on Terahertz Electronics. IRMMW-THz. Joint 32nd International Conference on

Print_ISBN

978-1-4244-1438-3

Type

conf

DOI

10.1109/ICIMW.2007.4516407

Filename

4516407