Title :
Stochastic Complexity for the Detection of Periodically Expressed Genes
Author :
Ciprian Doru Giurcaneanu
Author_Institution :
Tampere University of Technology, Institute of Signal Processing, P.O. Box 553, FIN-33101 Tampere, Finland. ciprian.giurcaneanu@tut.fi
fDate :
6/1/2007 12:00:00 AM
Abstract :
The problem we address in this study is to decide, based on the available measurements, if a particular gene exhibits a periodic behavior. To this end we propose a principled method relying on the Stochastic Complexity (SC) whose computation is discussed for the generalized Gaussian distribution. We also investigate the relationship between SC, the well-known Minimum Description Length (MDL) formula, and the Bayesian Information Criterion (BIC). The performances of the SC-based approach are compared for simulated and real data with methods that are widely accepted in the bioinformatics community.
Keywords :
"Stochastic processes","Gene expression","Gaussian distribution","Bayesian methods","Computational modeling","Stochastic resonance","Testing","Robustness","Shape","Frequency estimation"
Conference_Titel :
Genomic Signal Processing and Statistics, 2007. GENSIPS 2007. IEEE International Workshop on
Print_ISBN :
978-1-4244-0998-3
DOI :
10.1109/GENSIPS.2007.4365842