DocumentCode :
3643856
Title :
Two way clustering of microarray data using a hybrid approach
Author :
Raul Măluţan;Bogdan Belean;Pedro Gómez Vilda;Monica Borda
Author_Institution :
Communications Department, Technical University of Cluj-Napoca, 26-28 George Baritiu St., 400027 Cluj-Napoca, Romania
fYear :
2011
Firstpage :
417
Lastpage :
420
Abstract :
The Microarray technique is rather powerful, as it allows to test up thousands of genes at a time, but this produces an overwhelming set of data files containing huge amounts of data, which is quite difficult to pre-process, separate, classify and correlate for interesting conclusions to be extracted. Modern machine learning, data mining and clustering techniques based on information theory, are needed to read and interpret the information contents buried in those large data sets. Independent Component Analysis method can be used to correct the data affected by corruption processes or to filter the uncorrectable one and then clustering methods can group similar genes or classify samples. In this paper a hybrid approach is used to obtain a two way unsupervised clustering for a corrected microarray data.
Keywords :
"Clustering algorithms","Indexes","Probes","Algorithm design and analysis","Gene expression","Independent component analysis","Data analysis"
Publisher :
ieee
Conference_Titel :
Telecommunications and Signal Processing (TSP), 2011 34th International Conference on
Print_ISBN :
978-1-4577-1410-8
Type :
conf
DOI :
10.1109/TSP.2011.6043698
Filename :
6043698
Link To Document :
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