• DocumentCode
    3646919
  • Title

    Quasi-cyclic codes exhibiting the gene regulatory network of the cell cycle

  • Author

    Vida Ravanmehr;Bane Vasić

  • Author_Institution
    Department of Electrical and Computer Engineering, University of Arizona, Tucson, 85721, USA
  • fYear
    2012
  • fDate
    5/1/2012 12:00:00 AM
  • Firstpage
    412
  • Lastpage
    417
  • Abstract
    We present an artificial Boolean network exhibiting the behaviour similar to that of the cell cycle: three phases and checkpoints between them. The phases follow the increase of the cell mass, while checkpoints ensure that internal errors are corrected before moving to the next phase. The network can tolerate up to one gene mutation and one transient error in gene expressions. It has only 6 genes and is the smallest and simplest network with such behavior. It is based on a special type of error correction codes, resulting in an elegant and symmetric network topology and highly symmetric attractor basin.
  • Keywords
    "Vectors","Parity check codes","Decoding","Gene expression","Robustness","Transient analysis","Noise"
  • Publisher
    ieee
  • Conference_Titel
    Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2012 IEEE Symposium on
  • Print_ISBN
    978-1-4673-1190-8
  • Type

    conf

  • DOI
    10.1109/CIBCB.2012.6217259
  • Filename
    6217259