Title :
Control problems related to three compartmental model of combined anticancer therapy
Author :
Andrzej Swierniak
Author_Institution :
Department of Automatic Control, Silesian University of Technology, Gliwice, Poland, Akademicka 16, 44101
fDate :
7/1/2012 12:00:00 AM
Abstract :
We present control problems related to a three compartmental model of combinations of antiangiogenic treatment with chemotherapy. The line of reasoning is based on the idea of Hahnfeldt et al.(1999) with modifications resulting from the use of multiple modalities and effects of drug resistance. We present analysis of dynamic properties of the models and some simulation results for different treatment protocols.
Keywords :
"Tumors","Drugs","Mathematical model","Cancer","Biological system modeling","Analytical models"
Conference_Titel :
Control & Automation (MED), 2012 20th Mediterranean Conference on
Print_ISBN :
978-1-4673-2530-1
DOI :
10.1109/MED.2012.6265839