Title :
White matter injury in a newborn rat model analyzed with Resting-State Optical Imaging of Intrinsic Signals (rsOIS)
Author :
Edgar Guevara;Parikshat Sirpal;Maxime Abran;Philippe Pouliot;Frédéric Lesage;Chen Jin;Irene Londono;Gregory A. Lodygensky
Author_Institution :
Department of Computing, Electronics, and Mechatronics, Universidad de las Amé
fDate :
6/1/2015 12:00:00 AM
Abstract :
Using rsOIS (Resting-State Optical Imaging of Intrinsic Signals), we demonstrated a non-invasive approach to assess cerebral changes in response to inflammatory white matter injury. Surprisingly, lipopolysaccharide (LPS) exposure induced an increase in inter-hemispheric functional connectivity (fc); this may reflect a possible compensatory mechanism to overcome the effects of inflammatory insult.
Keywords :
"Injuries","Correlation","Pediatrics","Optical imaging","Rodents","Rats"
Conference_Titel :
Photonics North, 2015
DOI :
10.1109/PN.2015.7292523
