Title :
Electrochemistry provides a simple way to monitor Pseudomonas aeruginosa metabolites
Author :
Julie Oziat;Sylvie Elsen;Roisin M. Owens;George G. Malliaras;Pascal Mailley
Author_Institution :
CEA, Leti, MINATEC Campus, F-38054 Grenoble, France
Abstract :
Pseudomonas aeruginosa is one of the most common bacteria responsible for nosocomial infections. To imagine new therapies, understanding virulence mechanisms and the associated communication system of the bacterium (its quorum sensing) is a target of the first importance. Electrochemistry is a promising tool for real-time in situ monitoring of electroactive species issued from P. aeruginosa communication system. This contribution deals with the electrochemical characterization of the main bacteria electroactive metabolites: Pseudomonas Quinolone Signal, pyocyanin and 2´-aminoacetophenone. These metabolites were electrochemically characterized and further detected in supernatant of P. aeruginosa PA01 strain grown in LB medium.
Keywords :
"Electrodes","Oxidation","Electric potential","Microorganisms","Sensors","Carbon","Strain"
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE
Electronic_ISBN :
1558-4615
DOI :
10.1109/EMBC.2015.7320132