Flow and temperature control for an innovative hyperthermic intraperitoneal chemotherapy equipment

Nowadays cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC) represents a standard treatment for Peritoneal Carcinomatosis, a final stage of abdominal cancer. HIPEC requires the use of an equipment that delivers the cytostatic solution inside the peritoneal cavity at high temperature of 41°C-43°C. In this paper the authors present a temperature control structure for an innovative HIPEC equipment, that is under development. A discrete Internal Model Controller is designed for the cytostatic solution´s temperature control. Due to the fact that the heating process depends on the time the solution spends inside the heating element a feed-forward control structure in respect to the solution flow is also analyzed.