Title :
A simple and economical method for improving whole-genome alignment
Author :
Huijun Mai;Tak-wah Lam;Hing-fung Ting
Author_Institution :
HKU-BGI Bioinformatics Algorithms Research Lab, Department of Computer Science, University of Hong Kong, Hong Kong
Abstract :
The recent advancement of whole genome alignment software has made it possible to align two genomes very efficiently and with only a small sacrifice in sensitivity. Yet it becomes very slow if the extra sensitivity is needed. This paper proposes a simple but effective method to improve the sensitivity of existing whole-genome alignment software without paying much extra running time.
Keywords :
"Bioinformatics","Genomics","Sensitivity","Software","Dynamic programming","Mice","Software algorithms"
Conference_Titel :
Computational Advances in Bio and Medical Sciences (ICCABS), 2015 IEEE 5th International Conference on
DOI :
10.1109/ICCABS.2015.7344731
