Title :
Multiplex detection of IgG class antibodies to Toxoplasma gondii, Rubella virus, Cytomegalovirus and Herpes virus using a novel multiplex flow immunoassay
Author :
Sergey Dolgushin;Sergey Selishchev;Ekaterina Loseva;Elena Odintsova;Andrey Tronin
Author_Institution :
Biomedical Systems Department National Research University of Electronic Technology, Moscow Russia
Abstract :
Preclinical tests of a novel multiplex immunoassay for the detection of TORCH infections in human serum using flow cytometry are presented. The immunoassay is intended for the qualitative detection of specific human IgG class antibodies to Toxoplasma gondii, Rubella virus Cytomegalovirus and Herpes virus in human serum. Multiplex analysis is performed in vitro on polystyrene microspheres encoded with organic dye. The diagnostic sensitivity of the kit is evaluated to be not less than 95%.
Keywords :
"Immune system","Multiplexing","Fluorescence","Sensitivity","Suspensions","Biomedical optical imaging","Optical scattering"
Conference_Titel :
Biomedical Engineering and Computational Technologies (SIBIRCON), 2015 International Conference on
Print_ISBN :
978-1-4673-9109-2
DOI :
10.1109/SIBIRCON.2015.7361850
