Title :
Identification of amyloid plaques in mouse brain tissue slides using quantitative phase imaging
Author :
Moosung Lee;JaeHwang Jung;Eeksung Lee;Yong Jeong;YongKeun Park
Author_Institution :
Department of Physics, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea
Abstract :
We demonstrate that quantitative phase imaging (QPI) can detect amyloid plaques in the brain of Alzheimer´s disease (AD). Comparing QPIs and fluorescence images from wild-type and AD mice brains, we suggest that digital microscopic holography can be utilized for diagnosing AD.
Keywords :
"Mice","Fluorescence","Microscopy","Brain","Alzheimer´s disease"
Conference_Titel :
Lasers and Electro-Optics Pacific Rim (CLEO-PR), 2015 11th Conference on
DOI :
10.1109/CLEOPR.2015.7376448