Research on non-invasive glucose concentration measurement by NIR transmission

Diabetes is a widely spreading disease which is known as one of the life threatening disease in the world. It occurs not only among adults and elderly, but also among infants and children. Blood glucose measurements are indispensable to diabetes patients to determine their insulin dose intake. Invasive blood glucose measurement ways which are high in accuracy are common but they are uncomfortable and have higher risk of infections especially for elders, pregnant and children. As a change, non-invasive blood glucose measurement techniques are introduced to provide a reliable and pain free method for monitoring glucose level without puncturing the skin. In this paper, a non-invasive glucose monitoring setup was developed using near infrared by detecting the transmission laser power. The detecting system included the semiconductor laser diode as light source, the S302C light power probe which detected the incident light and, the PM100USB transmit data to the computer. The specific infrared spectrum (1310 nm) was used as the incident beam. A proportional relationship between the laser power and the glucose concentration was proved by comparing the resulting laser power for a few of glucose aqueous solution samples with glucose concentration estimated value at the same circumstances.