Title :
Aptasensor for diabetes mellitus detection and monitoring
Author :
Deanpen Japrung;Chayacon Apiwat;Kiatnida Treerattrakoon;Tararaj Dharakul;Patraporn Luksirikul
Author_Institution :
National Nanotechnology Center, National Science and Technology Development Agency, Thailand Science Park, Pathumthani, Thailand
fDate :
7/1/2015 12:00:00 AM
Abstract :
DNA aptamers against GHSA, which is protein marker for diabetes mellitus, were selected and modified. In combination properties of modified GHSA binding aptamer and fluorescence quenching of GO, we develop simple and sensitive platform for detection of GHSA in both PBS and human serum with the LOD of 50 μg/mL. We envision that our GO-aptamer platform has a potential to be GHSA detection for screening and monitoring diabetes mellitus.
Keywords :
"Fluorescence","DNA","Graphene","Proteins","Yttrium","Diabetes","Monitoring"
Conference_Titel :
Nanotechnology (IEEE-NANO) , 2015 IEEE 15th International Conference on
DOI :
10.1109/NANO.2015.7388933
