The renin-angiotensin and kinin-kallikrein systems between industrial and informational epochs. Conflict of defensive programmes: Pathogenic or sanogenic?

The solution of a number of pathophysiological problems emerged as a result of the so-called technological progress with the increasing use of technical equipment brought to the human mind a number of advantages: the use of a variety of external devices, which helped to minimize the internal efforts, thus leading to the acceleration of evolution and the production of intermediate elements placed between the external environment and the Homo, or in other words the creation of "artificial organs" that extend and enhance the properties of the anatomical organs. These two aspects explain the rapid adaptation of Homo to different climatic characteristics of the Earth compared to other representatives of the fauna, but this adaptation took place without significant changes in human biological features.