• DocumentCode
    3763086
  • Title

    Micropatterned three-dimensional culture in click-crosslinkable and photodegradable gelatin hydrogels

  • Author

    Masato Tamura;Fumiki Yanagawa;Shinji Sugiura;Toshiyuki Takagi;Kimio Sumaru;Toshiyuki Kanamori

  • Author_Institution
    Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Central 5th, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan
  • fYear
    2015
  • Firstpage
    1
  • Lastpage
    3
  • Abstract
    This paper reports a novel click-crosslinkable and photodegradable gelatin hydrogels, which is useful for micropatterned three-dimensional culture. The azide-modified gelatin was prepared by mixing gelatin with Azide-PEG4-NHS ester solutions. The DBCO-PC-4armPEG was synthesized by the reaction between NHS-PC-4armPEG and DBCO-PEG4-amine. PD-gelatin was performed by mixing solutions of azide-modified gelatin and DBCO-PC-4armPEG in a 1:1 ratio. We successfully demonstrated the micropatterning of the photodegradable gelatin hydrogels and cell encapsulation in these hydrogels.
  • Publisher
    ieee
  • Conference_Titel
    Micro-NanoMechatronics and Human Science (MHS), 2015 International Symposium on
  • Type

    conf

  • DOI
    10.1109/MHS.2015.7438240
  • Filename
    7438240
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3763086