Origami microfluidics integrated with gold micropatterns

In this report, we show a concept of 3D microfluidic device by folding parylene layers with gold pattern in a microfluidic channel. Recently, we have proposed origami-3D microfluidic device. In this device, multi-layer fluidic channels were fabricated only by folding 2D-pattern. This simple process enables us to integrate several fluidic channel into a small chip. This report shows that gold layer was patterned in the origami-microfluidic devices. We believe that our fabrication method will contribute to the development of biomolecule analysis, because gold layer can potentially immobilize biomolecules, such as protein and DNA.