• DocumentCode
    3763468
  • Title

    Detection of base pair charges during DNA extension with Si nanowire FETs towards DNA sequencing

  • Author

    Yuchen Liang;Silu Zhang;Walter Hu

  • Author_Institution
    Dept. of Electrical Engineering, University of Texas at Dallas, Richardson, TX 75080, USA
  • fYear
    2015
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Designed DNA templates were anchored onto the surface of Si nanowire (SiNW) FETs. Then base pair (BP) extension reactions were performed on the DNA templates. The charges of newly formed BPs induced shifts of device Id-Vg curves. Vg shifts linearly with the number of BPs with a strong signal of ?10 mV/BP, indicating a great potential for DNA sequencing by detecting intrinsic charges of DNA backbones.
  • Publisher
    ieee
  • Conference_Titel
    Nanotechnology Materials and Devices Conference (NMDC), 2015 IEEE
  • Type

    conf

  • DOI
    10.1109/NMDC.2015.7439279
  • Filename
    7439279
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3763468