Title :
Modeling aspects of hemorrhage and hemodilution
Author :
Kaya, Mehmet ; Li, John K-J.
Author_Institution :
Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA
Abstract :
A model is developed to calculate the interactions and effects of continuing hemorrhage or hemodilution during surgery and transfusion, and utilizes the distinction between different types of fluids used, and their differential clinical effects as well as taking into account complex compensatory mechanisms such as Starling´s transcapillary refill. The basic prerequisite for preserving tissue oxygenation during hemodilution is adequate oxygen delivery and therefore all determinants of oxygen transport should be monitored
Keywords :
blood; haemodynamics; haemorheology; physiological models; surgery; Starling´s transcapillary refill; adequate oxygen delivery; blood pressure; complex compensatory mechanisms; continuing hemorrhage; crystalloids; differential clinical effects; fluid resuscitation; haemodilution; hematocrit; hemorrhagic shock; interstitial spaces; intravascular spaces; mass balance equations; mixed body fluid compartments; model; plasma volume; red blood cell volume; surgery; tissue oxygenation; transfusion; Biomedical engineering; Blood pressure; Cardiology; Colloidal crystals; Electric shock; Equations; Hemorrhaging; Plasmas; Red blood cells; Surgery;
Conference_Titel :
Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast
Conference_Location :
Philadelphia, PA
Print_ISBN :
0-7803-7419-3
DOI :
10.1109/NEBC.2002.999523
