Title :
Analysis of HIV proteins using DSP techniques
Author_Institution :
Dept. of Electr. & Comput. Syst. Eng., Monash Univ., Clayton, Vic., Australia
Abstract :
Our previous studies suggested that digital signal processing methods can be used to analyse linear sequences of amino acids to reveal the functional informational within the protein sequence. In this study both spectral and time-frequency methods are applied to the analysis of the functional content of HIV virus envelope proteins. Here, we have identified specific RRM frequency of HIV proteins, predicted active sites in these proteins and compared these predictions with experimentally determined active sites.
Keywords :
biochemistry; medical signal processing; molecular biophysics; proteins; spectral analysis; time-frequency analysis; CD4 molecule; HIV proteins analysis; HIV virus envelope proteins; acquired immunodeficiency syndrome; amino acids sequences; cell depletion; digital signal processing methods; experimentally determined active sites; functional informational; host cells infection; human immunodeficiency virus; predicted active sites; Amino acids; Continuous wavelet transforms; Digital signal processing; Frequency; Human immunodeficiency virus; Peptides; Proteins; Resonance; Sequences; Wavelet transforms;
Conference_Titel :
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
Print_ISBN :
0-7803-7211-5
DOI :
10.1109/IEMBS.2001.1017392
