• DocumentCode
    380555
  • Title

    Neurogenesis of respiratory rhythm: a computational study

  • Author

    Rybak, I.A. ; Paton, J.F.R. ; -John, W. M St

  • Author_Institution
    Sch. of Biomed. Eng., Drexel Univ., Philadelphia, PA, USA
  • Volume
    1
  • fYear
    2001
  • fDate
    2001
  • Firstpage
    810
  • Abstract
    Results of computational modeling of the respiratory rhythm generation have been used for analysis of the conditions that may define a network-based vs. a pacemaker-driven rhythm-generating mechanism. The possible cellular and network factors contributing to the transitions between the network-based and pacemaker-driven oscillations are discussed in connection with experimental data obtained its vivo, in situ and in vitro.
  • Keywords
    biomembrane transport; brain models; neural nets; neurophysiology; pneumodynamics; brainstem; cellular factors; computational study; experimental data; functionally different populations; gasping; inhibitory interactions; ionic channels; network factors; pacemaker-driven oscillations; pacemaker-driven rhythm-generating mechanism; respiratory neurons; respiratory rhythm neurogenesis; Biomedical computing; Cellular networks; Computational modeling; Computer networks; In vitro; In vivo; Neurons; Pacemakers; Physiology; Rhythm;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
  • ISSN
    1094-687X
  • Print_ISBN
    0-7803-7211-5
  • Type

    conf

  • DOI
    10.1109/IEMBS.2001.1019064
  • Filename
    1019064