• DocumentCode
    380556
  • Title

    Bursting of neurons under slow wave stimulation

  • Author

    Zhu, Jun-Ling ; Shen, Qiang ; Jiang, Da-Zong

  • Author_Institution
    Inst. of Biomed. Eng., Xi´´an Jiaotong Univ., China
  • Volume
    1
  • fYear
    2001
  • fDate
    2001
  • Firstpage
    814
  • Abstract
    Hopf bifurcation of the H-H neuron was computed by numerical methods and discharge of H-H neuron under slow wave stimulation was studied by simulation. It is shown that slow wave can result in neuron bursting, especially the long time-course bursting, and onset of the bursting is related with Hopf bifurcation. The results prompt that bursting and supernormal excitability of neurons can be induced by slow excitatory synaptic reaction when it is big enough. This phenomenon probably can be used to explain the seizure of some diseases (such as epilepsy).
  • Keywords
    bioelectric potentials; cellular biophysics; neurophysiology; physiological models; H-H neuron; Hodgkin-Huxley neuron; Hopf bifurcation; epilepsy; neurons bursting; numerical methods; seizure; slow excitatory synaptic reaction; slow wave stimulation; supernormal excitability; Bifurcation; Biomedical computing; Biomedical engineering; Biomembranes; Computational modeling; Diseases; Epilepsy; Frequency; Mathematical model; Neurons;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
  • ISSN
    1094-687X
  • Print_ISBN
    0-7803-7211-5
  • Type

    conf

  • DOI
    10.1109/IEMBS.2001.1019065
  • Filename
    1019065