DocumentCode
380556
Title
Bursting of neurons under slow wave stimulation
Author
Zhu, Jun-Ling ; Shen, Qiang ; Jiang, Da-Zong
Author_Institution
Inst. of Biomed. Eng., Xi´´an Jiaotong Univ., China
Volume
1
fYear
2001
fDate
2001
Firstpage
814
Abstract
Hopf bifurcation of the H-H neuron was computed by numerical methods and discharge of H-H neuron under slow wave stimulation was studied by simulation. It is shown that slow wave can result in neuron bursting, especially the long time-course bursting, and onset of the bursting is related with Hopf bifurcation. The results prompt that bursting and supernormal excitability of neurons can be induced by slow excitatory synaptic reaction when it is big enough. This phenomenon probably can be used to explain the seizure of some diseases (such as epilepsy).
Keywords
bioelectric potentials; cellular biophysics; neurophysiology; physiological models; H-H neuron; Hodgkin-Huxley neuron; Hopf bifurcation; epilepsy; neurons bursting; numerical methods; seizure; slow excitatory synaptic reaction; slow wave stimulation; supernormal excitability; Bifurcation; Biomedical computing; Biomedical engineering; Biomembranes; Computational modeling; Diseases; Epilepsy; Frequency; Mathematical model; Neurons;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
ISSN
1094-687X
Print_ISBN
0-7803-7211-5
Type
conf
DOI
10.1109/IEMBS.2001.1019065
Filename
1019065
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