Laser-Doppler blood-flowmetery modeling by Monte Carlo method

Laser Doppler flowmetery (LDF) is a noninvasive method to assess tissue blood flow. Previously published works have proposed a mathematical model for LDF and showed that there is a relationship between the first moment of the power spectrum and the velocity of moving blood cells (MBCs). Also researchers have studied this method by mathematical analyses in various aspects. In this paper a new model for LDF measurement of blood perfusion at the skin is proposed. It is based on the Monte Carlo method and simulation of photon transmission through the tissue. We have shown that this new model is more flexible and provides better agreement with the experimental results. For example this model represents the nonlinear relationship between the first moment of the power spectrum and the blood cell velocity which is not seen in previous models.